covid-19 ASSAYS and studies

IITRI is in custody of a SARS-CoV-2 strain responsible for COVID-19.

We now offer both in vitro and in vivo options for testing your candidates for the inhibition of SARS-CoV-2 as well as efficacy::

– Vero cell SARS-CoV-2 assays are conducted in BSL-3 containment to determine efficacy (cell survival endpoints being EC50 and TC50). Vero cells are infected with the SARS-CoV-2 virus in 96 well plates and 50% are treated with your test article at various concentrations.

– Testing of surface disinfectant sprays and sanitizers against the SARS-CoV-2 strain. IITRI is currently conducting this type of testing based on a standard industry protocol.

– COVID-19 Ferret model studies to determine changes in viral load and shedding after intranasal administration of the SARS-CoV-2 virus. Therefore this model is a SARS-CoV-2 infection model. Intranasal, inhaled (inhalation) and other routes of administration are offered for dosing your test article. 

-COVID-19 Syrian hamster model to determine changes in viral load, shedding, and body weight metrics. Multiple routes of administration are available for your test article.

IITRI has established itself as a leading COVID-19 CRO and due to the importance for this testing during the pandemic, has made provisions to turn these assays and studies around rapidly.

Contact Us for more detailed information, to discuss with a PhD study director or request a cost estimate.