COVID-19 Syrian hamster model
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covid-19 Syrian hamster model
Below is a basic study description and design, although IITRI can provide specialized study designs based on your needs. Contact us today to learn more and discuss how we can partner for SARS-CoV-2 animal studies.
|Species Information||Syrian Hamster (~5-6 weeks at challenge)|
|Study Duration||Sponsor dependent (14+ normal)|
|Challenge Dosage and Strains||
Intranasal (25 μl / nare) at 5 x 10^4; wildtype USA-WA1/2020), relevant variants
|Drug administration||Aerosol, PO, IN, SC (inquire about others)|
ID50=2-5E2 TCID50, recommended 5-10xID50= 1-5E3to4 TCID50
– Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility (Clinical Infectious Diseases 03/2020)