Immunology

The IITRI team is ready with immunology services to support drug development from discovery and preclinical development through analysis of human clinical trial samples. We utilize both in vitro and in vivo assays to analyze the immune response of biologic, antiviral and antibacterial drugs, vaccines, and adjuvants. This testing can be broken down into two key areas, immunogenicity testing and immunotoxicology.

Core Services

Immunogenicity

Immunophenotyping

  • Flow cytometry analysis (FACS)
  • Cell population dynamics and infiltration
  • Mucosal immunology
  • Cell cycle analysis

Immunotoxicology

  • Immunophenotyping of cytokines
  • Plaque forming cell assay
  • Natural killer assay
  • Macrophage studies
  • In vivo host defense models
  • Murine local lymph node assay
  • Lymphocyte blastogenesis/ proliferation assay
  • Cytotoxic T-lymphocyte assay

The IITRI Advantage

  • Highly skilled and experienced scientific team with over 50% of the scientists holding advanced degrees
  • Extensive experience in evaluating the immune response of vaccines and antivirals
  • Expertise in GLP and GMP ELISA method development and validation
  • Personalized program design for non-standard and customized studies