Generated by All in One SEO v5.0.0.1, this is an llms.txt file, used by LLMs to index the site. # IITRI Advancing Science Together ## Sitemaps - [XML Sitemap](https://iitri.org/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [Find IITRI at the RRPV and Options Meetings in August!](https://iitri.org/2026/08/05/barda-rrpv-options-flu-meetings-august-2026/) - IITRI is attending the BARDA RRPV General Membership Meeting and ISRV Options for the Control of Influenza XIII Conference this Aug/Sept! See you there! - [IITRI Attended ICTR Conference Here in Chicago](https://iitri.org/2026/06/08/ictr-2026/) - IITRI attended the Innovations in Countermeasures & Toxicology Research (ICTR) Conference in Chicago at the Northwestern University from June 1-3 on MCMs. - [IITRI Attending ICAR Meeting in Prague!](https://iitri.org/2026/04/24/icar-2026/) - IITRI will attend the 39th International Conference on Antiviral Research (ICAR) meeting from Monday, April 27th to Friday, May 1st in Prague, Czech Republic! - [IITRI Attending RRPV Meeting in Arlington, VA!](https://iitri.org/2025/08/12/rrpv-2025/) - IITRI will attend the 2nd Annual General Membership Meeting for the BARDA Rapid Response Partnership Vehicle (RRPV) consortium in Arlington, VA on August 26-27. - [Histotechnology Professionals Day Spotlight: IITRI's Histology and Necropsy Services](https://iitri.org/2026/03/10/histology-and-necropsy-spotlight/) - At IITRI, on Histotechnology Professionals Day (HPD), we are thankful for the supporting GLP histology and necropsy services provided by our internal team. - [Stop by the IITRI Booth at SOT in March!](https://iitri.org/2026/01/08/iitri-sot-2026/) - We are excited once again to participate in the SOT ToxExpo during the 65th Annual Meeting in San Diego from March 22-25. Find us at Booth 1402 by the entrance! - [Will We See You at ACT in Nov?](https://iitri.org/2025/10/23/iitri-act-2025/) - IITRI will attend the 46th annual ACT meeting (Phoenix, AZ). Booth 403 on November 17 from 9am - 6:30pm, and November 18 from 8am-6:30pm. See you there! - [Spotlight: Government Grants and Contracts Support](https://iitri.org/2023/09/01/gov-grant-contract-support/) - IITRI has supported government grants and contracts for NCI, NIAID, NIH, CDC, BARDA, and DOD and can support projects for the newly created ARPA-H as well now - [New Sponsor Publications: Influenza and Opioid Treatments](https://iitri.org/2025/04/11/new-publications-sponsors-nature/) - IITRI is proud to share new publications from in vivo research in mice and NHPs performed at IITRI and published by our Sponsors. Congrats! - [New Partner Publications- Promising COVID-19 Studies](https://iitri.org/2021/07/07/new-publications-from-iitri-partners/) - [et_pb_section fb_built=”1″ _builder_version=”4.16″ custom_margin=”-1px|||||” custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”||28px|||” global_colors_info=”{}”] IITRI is proud to share the promising news from multiple sponsors of COVID-19 in vitro and in vivo studies. Links below to press releases and recent publications. Congrats all! New IITRI - [IITRI's Clinical Trial Support Services In the News](https://iitri.org/2014/09/01/clinical-trial-support-services-news/) - IITRI offers a wide range of BioA services for the detection and quantification of small molecule and biologic drug candidates from human clinical trial samples - [$9 million for the NCI PREVENT Cancer Program Contract](https://iitri.org/2015/09/26/iitri-awarded-prevent-cancer/) - IIT Research Institute has been awarded a contract for up to $9 million for preclinical services to support the National Cancer Institute (NCI) Program - [NCI Awards IITRI $29.8 Million for 2 New Programs](https://iitri.org/2016/07/05/iitri-awarded-new-preclinical-progr/) - The National Cancer Institute’s Division of Cancer Treatment and Diagnosis (DCTD) has awarded IITRI $29.8 million for two major 5-year new programs. - [IITRI Awarded Over $4.7M BARDA Contracts](https://iitri.org/2016/09/29/iitri-awarded-over-4-7m-barda-contracts/) - IITRI announces the recent award of three major new programs by the Biomedical Advanced Research and Development Authority (BARDA) valued at more than $4.7 M. - [Promising antiviral activity of Moleculin's drug candidate](https://iitri.org/2020/08/05/antiviral-activity-of-moleculins-candidate/) - IITRI saw antiviral activity from one of our partner's drug candidate for COVID-19 in our contracted in vitro study - [Sponsor News: Antiviral activity of Ascletis' candidates against SARS-CoV-2](https://iitri.org/2022/04/19/sponsor-news-antiviral-activity-ascletis/) - Promising news from a partner on the vitro testing of drug candidates for antiviral effects against SARS-CoV-2 performed at IITRI - [Partner News: NCI Project Team Award for Inhaled COVID-19 Candidate APN-01](https://iitri.org/2022/09/23/partner-news-nci-inhaled-covid-drug/) - IITRI's collaboration with National Cancer Institute contributed to NCI team receiving award for inhaled COVID-19 drug candidate APN01 - [Sponsor News: Ascletis U.S. IND Filing of Antiviral ASC10 for MPX](https://iitri.org/2022/10/26/sponsor-news-monkeypox-ind-ascletis/) - IND filing by a Sponsor using data from in vitro testing of drug candidates for antiviral effects against monkeypox performed at IITRI - [IITRI Highlights: SARS-CoV-2 Publication and New DABTs](https://iitri.org/2022/12/22/iitri-team-publications-and-dabts/) - IITRI celebrates our Virology and Toxicology teams recent accomplishments for SARS-CoV-2 articles and new DABTs. - [IITRI Research In Peer-Reviewed Publications](https://iitri.org/2024/12/10/recent-iitri-research-published/) - IITRI microbiology and molecular biology team's contract infectious animal model research was recently highlighted in multiple peer reviewed publications - [Meet with IITRI at SOT in Orlando!](https://iitri.org/2025/03/05/iitri-sot-2025/) - IITRI is attending the 64th annual SOT meeting in Orlando, FL at Booth 902 near the entrance of the ToxExpo from 9am - 4:30pm on March 17-19. - [Service Update: SARS-CoV-2 Studies Allowed Under BSL-2](https://iitri.org/2025/02/12/sars-cov-2-now-bsl-2/) - New guidance from the CDC and NIH now permit handling SARS-CoV-2 under Biosafety Level 2 (BSL-2) conditions for specific research in vitro and in vivo - [World Cancer Day Spotlight: IITRI's Cancer Research Programs](https://iitri.org/2025/02/04/world-cancer-day-research/) - IITRI's dedicated cancer research program in 1957 has been instrumental in evaluating the efficacy and safety of cancer therapies, with over 250 publications. - [Service Spotlight : Vaccine Challenge and Toxicology Studies](https://iitri.org/2021/08/24/service-spotlight-vaccine-development/) - Vaccine development, animal challenge models, GLP toxicology, and immunogenicity studies to meet FDA submission guidelines. - [Will We See You At SOT 2023?](https://iitri.org/2023/02/21/sot-nashville-2023/) - IITRI is attending the 62nd Meeting for SOT (Mar 19-23) in Nashville. You can find us in the exhibit hall at Booth #602 from 9am - 4:30pm. - [IITRI Announces New Flow Cytometry Services](https://iitri.org/2017/07/17/new-flow-cytometry-services/) - IITRI is pleased to announce the addition of immunophenotyping services using flow cytometry to our ex vivo assay offerings. - [Visit Us at ACT Tox 2024!](https://iitri.org/2024/09/11/act-tox-2024/) - Visit with our Tox and BD teams in Austin for the American College of Toxicology Meeting and Expo Live! Nov 17-20 at Booth 406. - [Will We See You at the RRPV Meeting August 13-14?](https://iitri.org/2024/07/24/barda-rrpv-meeting-aug24/) - IITRI will attend the Inaugural General Membership Meeting for the BARDA Rapid Response Partnership Vehicle (RRPV) consortium in Washington, DC, on August 13-14 - [Service Spotlight: Drug-Resistant Pathogen Studies](https://iitri.org/2023/03/22/service-spotlight-drug-resistant-studies/) - IITRI is a leading provider of efficacy studies for pathogens such as drug-resistant bacteria or fungi in BSL-2 and BSL-3 - [Service Spotlight: Ferret Influenza Transmission Studies](https://iitri.org/2024/07/15/service-spotlight-ferret-influenza-transmission-studies/) - Experts in ferret challenge studies and transmission models for influenza. Testing for relevant strains such as H1N1 and H5N1 and new emerging viruses. - [Navigating Preclinical Services for Animal Rule Studies](https://iitri.org/2024/05/02/animal-rule-studies/) - For pharmaceutical and biotech companies embarking on Animal Rule studies involving BSL-2 and BSL-3 pathogens, partnering with specialized CROs is critical. - [Join Us at SOT 2024 in Salt Lake City!](https://iitri.org/2024/01/11/join-us-at-sot-2024-in-salt-lake-city/) - IITRI is exhibiting and attending the Society of Toxicology meeting in Salt Lake City, Utah March 10-14. Find us at Booth 901. - [Meet with us at ASV and ACT this year!](https://iitri.org/2022/06/15/asv-and-act-2022/) - IITRI team will be at the American Society for Virology in Madison, WI in July and American College of Toxicology in Denver, Co in November. - [Service Spotlight- Carcinogenicity Studies](https://iitri.org/2022/02/25/spotlight-carc-studies/) - Expert CRO services for both 2-year rodent and 6-month rasH2 transgenic mouse carcinogenicity studies with large historical databases. - [See You Soon at the SOT Annual Meeting in San Diego!](https://iitri.org/2022/02/15/sot-2022-san-diego/) - We'll be attending the 2022 SOT meeting and ToxExpo on March 27-31. Hope to see you there too! - [Service Spotlight: Exposure Atmosphere Characterization](https://iitri.org/2021/07/26/spotlight-atmosphere-characterization/) - Exposure generation and characterization service for method development and preliminary inhalation toxicology studies - [SARS-CoV-2 Variants of Concern Now Available](https://iitri.org/2021/04/22/sars-cov-2-variants/) - SARS-CoV-2 Variants of Concern (VOC): B.1.1.7 (UK), B.1.351 (South Africa), P.1 (Brazil) available for use in assays and animal models - [IITRI offering the hACE2 mouse model for COVID-19](https://iitri.org/2020/11/24/iitri-hace2-mouse-covid-19/) - IITRI offers the hACE2 transgenic mouse model, ferret model, and syrian golden hamster model for COVID-19 studies - [Hamster and ferret models available for COVID-19 studies](https://iitri.org/2020/08/06/hamster-and-ferret-models-covid-19-studies/) - IITRI has developed a Syrian hamster and ferret model for COVID-19 studies, and the hACE2 transgenic mouse model is in development. - [IITRI is testing antivirals and vaccines for COVID-19 | CRO](https://iitri.org/2020/03/19/antivirals-and-vaccines-covid-19/) - IITRI is now in custody of the SARS-CoV-2 strain responsible for COVID-19, and is looking to test antiviral and vaccine candidates. - [Society of Toxicology 59th Annual Meeting and ToxExpo](https://iitri.org/2020/03/04/society-of-toxicology-59th-meeting/) - The Society of Toxicology (SOT) meeting has been cancelled due to ongoing concerns over the spread of COVID 19. - [American College of Toxicology 40th Annual Meeting](https://iitri.org/2019/10/22/act-40th-meeting/) - Meet with our Business Development and Toxicology leadership at the 40th Annual Meeting of the American College of Toxicology. - [Service Spotlight: Aerosol Studies in NHPs](https://iitri.org/2023/07/18/nhp-aerosol-drug-delivery-services/) - IITRI has advantage of expertise with NHP models and comprehensive preclinical inhalation services for efficacy, safety, and toxicology - [Visit Our Virology Team's Poster Presentation at ASV!](https://iitri.org/2023/06/20/asv-covid-hamster-presentation/) - IITRI's virology team will be presenting a poster on the SARS-CoV-2 Syrian hamster model at the ASV meeting in Georgia this weekend. - [American College of Toxicology (Virtual) 41st Meeting](https://iitri.org/2020/10/26/act-virtual-meeting-2020/) - Visit IITRI's booth at the ACT 2020 virtual meeting from Nov 16-18 and chat live about your toxicology program needs - [2020 ASM Biothreats](https://iitri.org/2019/10/22/2020-asm-biothreats/) - IITRI attending ASM Biothreats meeting in 2020. - [Dave McCormick at Science2Startup: New Sleep Apnea Drugs](https://iitri.org/2019/04/12/science2startup-sleep-apnea/) - David McCormick to present on the development of novel agents to treat sleep-disordered breathing (apnea) at the Science2Startup (S2S) symposium in Cambridge. - [We'll be at the American College of Toxicology Meeting from Nov 13-16!](https://iitri.org/2022/10/24/act-am2022-denver/) - IITRI will be at the American College for Toxicology meeting November 13-16 at the Gaylord Rockies. Meet with us there! - [Immunostain SARS-CoV-2 Efficacy Assay Available](https://iitri.org/2021/01/27/immunostain-covid-efficacy-assay/) - IITRI offers an efficacy assay using an immunostain in BSL-3 for effects of drugs on SARS-CoV-2. Cytox assay still available in BSL-2. - [Division Spotlight: Inhalation Toxicology](https://iitri.org/2021/03/24/blog-inhalation-toxicology/) - 40+ Years of Experience in GLP Inhalation Studies including inhaled drugs, infectious aerosol challenges, environmental risk, and e-cig or flavor studies. - [ACT 2023 is Next Month!](https://iitri.org/2023/10/06/act-tox-2023/) - IITRI will be at the 44th American College of Toxicology meeting in Orlando, Nov 12-15. You can find us in the Expo hall at Booth #105 on Monday and Tuesday. - [World Vaccine & Immunotherapy Congress](https://iitri.org/2019/10/22/world-vaccine-congress/) - IITRI at the World Vaccine & Immunotherapy Congress Booth #15, December 2-5, 2019, San Francisco, CA - [IITRI-Vaccine-Antiinfectives-Lunch-n-Learn](https://iitri.org/2018/08/21/antiinfectives-lunch-n-learn/) - Dr. Robert Baker gave a Lunch-n-Learn on Regulatory Approval Pathways for Vaccines and Antivirals: Laying the Groundwork at Mass Bio 2018 - [Zika Poster Presentation at ASM Biothreats 2018 Meeting](https://iitri.org/2018/01/08/zika-poster-asm-2018/) - IITRI will be presenting a poster at the ASM Biothreats 2018 Meeting, February 12-14 in Baltimore, MD on the Zika model - [Zika Virus (ZIKV) Mouse Pregnancy Model Now Available](https://iitri.org/2017/07/25/zikv-mouse-pregnancy-model/) - Mouse pregnancy model is available to evaluate vaccines or antivirals for protection against Zika virus maternal-fetal transmission and resulting fetal defects - [IITRI Announces Expansion of Immunology Capabilities](https://iitri.org/2017/05/02/expansion-immunology-capabilities/) - IITRI is pleased to announce the expansion of our infectious disease immunology capabilities with the recent hiring of Justin Richner, PhD - [IITRI Chosen As Member of Nonclinical Studies Network](https://iitri.org/2017/03/31/iitri-selected-nonclinical-studies-network/) - IITRI was chosen as a member of a Nonclinical Studies Network created by BARDA to aid in the development of medical countermeasures for biological threats - [ASCO 2016 Poster with Singh Biotechnology, LLC](https://iitri.org/2016/06/13/asco-2016-poster/) - IITRI co-authored a poster presented at the recent American Society of Clinical Oncology (ASCO) meeting in Chicago, IL. - [IITRI at IMED Meeting on Zika Mouse and Macaques Models](https://iitri.org/2016/10/03/iitri-presenting-imed/) - IITRI will be presenting at the International Meeting on Emerging Diseases and Surveillance (IMED) Nov 4-7, 2016 in Vienna on Zika Mouse and NHP Models - [IITRI Announces Membership in NCBD Consortium](https://iitri.org/2016/05/26/iitri-joins-ncbd/) - ITRI is pleased to announce our acceptance as a member into the National Chemical & Biological Defense Consortium (NCBDC). - [IITRI Announces Zika Mouse Model Available](https://iitri.org/2016/05/09/new-zika-mouse-model/) - IIT Research Institute (IITRI) scientists have developed a novel mouse model for Zika using the viral strain responsible for outbreaks in Central/ South America - [Poster: Rabbit Aerosol Infection Model for anthrax](https://iitri.org/2016/02/19/asm-rabbit-aerosol-anthracis/) - A new IITRI poster presented at the recent ASM Biodefense and Emerging Diseases 2016 meeting forRabbit Aerosol Model for B. anthracis - [IITRI Welcomes Robert Baker PhD as Division Manager](https://iitri.org/2016/01/15/iitri-welcomes-robert-baker/) - Please join us in welcoming Robert Baker, PhD as Assistant Vice President and Manager of the Microbiology and Molecular Biology Division - [Expansion of ABSL-3 NHP Capacity at IITRI](https://iitri.org/2017/08/11/absl-3-nhp/) - IITRI now has expanded animal biosafety level 3 (ABSL-3) capacity to conduct pathogen challenge studies for vaccines or therapeutics in non-human primates (NHP) - [Dave McCormick Presenting at Eurotox 2017](https://iitri.org/2017/09/05/dave-mccormick-presenting-eurotox-2017/) - Dave McCormick, IITRI's Director, will be presenting at Eurotox 2017 in a symposium session: Toxicology and Cellular Mechanisms of Electromagnetic Fields (EMF) - [Notable contracts: Biological Surety Support for Plague Vaccine](https://iitri.org/2014/03/01/plague-vaccine/) - [et_pb_section admin_label=”section”] [et_pb_row admin_label=”row”] [et_pb_column type=”4_4″][et_pb_text admin_label=”Text”]Please click here for the article.[/et_pb_text][/et_pb_column] [/et_pb_row] [/et_pb_section] ## Pages - [Home](https://iitri.org/) - Preclinical CRO specializing in GLP toxicology and safety studies, IND-enabling programs, infectious disease vaccine and therapeutic development, and inhalation - [IITRI Advantage](https://iitri.org/iitri-advantage/) - IITRI offers a highly experienced team across toxicology, analytical chemistry, infectious disease, and QA to support preclinical drug development programs to the highest degree. - [Careers](https://iitri.org/careers/) - Join our team! IITRI career opportunities are updated frequently, please check back often. We offer competitive salary and benefits and are an EEO. - [Medical Devices](https://iitri.org/medical-devices/) - IITRI can provide services for preclinical medical device testing, and our experienced staff can work closely with you to develop customized study designs. - [Genetic Toxicology Studies](https://iitri.org/genetic-toxicology-studies/) - IITRI offers genetic toxicology testing to screen for mutations or chromosomal damage induced by a test article according to FDA, ICH, and OECD guidelines. - [IND-enabling studies](https://iitri.org/ind-enabling-studies/) - GLP-compliant, IND-enabling toxicology and safety programs to support regulatory submissions for small molecules, biologics, gene therapies, and vaccines. - [Toxicology](https://iitri.org/toxicology/) - IITRI is a premier provider of preclinical toxicology and safety services, with 40 years of experience conducting GLP studies for regulatory submissions. - [Reproductive Toxicology](https://iitri.org/developmental-and-reproductive-toxicology/) - IITRI offers developmental and reproductive toxicology studies in rats and rabbits, including inhalation and OECD studies, meeting FDA requirements. - [Histology and Necropsy Services](https://iitri.org/histology-and-necropsy-services/) - GLP compliant preclinical histology and histopathology support with on-site and travel services including for BSL-3 and inhalation toxicology in vivo histology. - [Services](https://iitri.org/services-2/) - IITRI offers GLP-compliant preclinical research services for infectious disease, inhalation toxicology, general toxicology, and bioanalytical support. - [Biodefense and Infectious Disease](https://iitri.org/biodefense-and-infectious-disease/) - Leading provider of infectious disease contract research services including immunogenicity, efficacy, potency, safety of vaccines, antivirals and therapeutics - [Peer-Reviewed Journal Publications](https://iitri.org/peer-reviewed-journal-publications/) - IITRI scientists are highly published in the areas of toxicology, inhalation toxicology, infectious disease, and analytical chemistry. - [Contact Us](https://iitri.org/contact-us/) - We'd love to hear from you. Please fill out the form or call us at 312-567-4487 to plan your next toxicology, infectious disease, inhalation, or BioA study. - [Bioanalytical](https://iitri.org/bioanalytical-services/) - IITRI offers bioanalytical laboratory services including method development and validation for the determination of small molecule or biologic drugs in complex tissues and fluids for preclinical studies. - [Bioanalytical Method Development and Validation](https://iitri.org/bioanalytical-method-development/) - Analytical method development and validation for small molecules, biologics, and drug products - [About Us](https://iitri.org/about-us/) - IITRI is a preclinical CRO offering GLP-compliant IND-enabling tox studies including inhalation, vaccine & infectious disease therapeutic development, and bioA - [Management Team](https://iitri.org/management-team-links/) - IITRI's management team includes the president and CEO, division managers, QA, and business development teams. - [Grant Support](https://iitri.org/grant-support/) - IITRI offers drug development grant support for startup biotechnology and academic researchers who are submitting SBIR, STTR, R01, and R21 applications for IND-enabling toxicology funding. - [Contact form - ACT Booth 403 (2025)](https://iitri.org/contact-form-tradeshow/) - Meet with us at SOT 2025 in Orlando at Booth 902? Fill out our form to contact IITRI! - [Institutional Biosafety Committee (IBC) Meeting Minutes](https://iitri.org/institutional-biosafety-committee-ibc-meeting-minutes/) - IITRI’s Institutional Biosafety Committee (IBC) meeting minutes page per latest NIH guidelines on approved meeting minutes for public access and transparency. - [Preclinical Development](https://iitri.org/preclinical-development/) - IITRI is a preclinical CRO offering customized preclinical development programs tailored to your drug candidate and timeline in compliance with FDA guidelines. - [NDA-Enabling Studies](https://iitri.org/nda-enabling-studies/) - IITRI offers comprehensive GLP toxicology services to support NDA filings including carcinogenicity and developmental and reproductive toxicology studies. - [Immunology Services](https://iitri.org/immunology-services/) - Preclinical immunology CRO expertise in in-vitro assays for small molecule, biologic, gene therapy, and vaccine development from discovery to IND submissions. - [Infectious Disease Animal Models](https://iitri.org/infectious-disease-animal-models/) - IITRI offers preclinical animal efficacy models for infectious diseases in rodents, rabbits and nonhuman primates, including select agents and MDR bacteria. - [Y. pestis Murine Bioaerosol Animal Model](https://iitri.org/y-pestis-murine-bioaerosol-animal-model/) - Aerosol studies in the BALB/c mouse model of Yersinia pestis for pneumonic plague. Nose-only generation and exposure for vaccine or treatment study challenges. - [COVID-19 Vaccine and Antiviral Development](https://iitri.org/covid-19-assays-and-studies/) - Leading CRO testing antivirals against SARS-CoV-2 in vitro and in K18-hACE2 mouse, Syrian hamster, and ferret models. Transmission and aerosol admin available. - [Zika Animal Models](https://iitri.org/zika-animal-models/) - Three specialized Zika virus models for research and testing purposes: rhesus macaque (NHP) model, AG129 mouse model, and mouse pregnancy model. - [Scientific News and Publications](https://iitri.org/scientific-news-publications-press/) - Read about recent IITRI publications and scientific news in the press! - [Upcoming Events](https://iitri.org/upcoming-events/) - Meet with IITRI at upcoming tradeshows and conferences, and speak with our toxicologists, immunologists, virologists, and microbiologists. - [Vaccine Toxicology](https://iitri.org/vaccine-toxicology/) - GLP vaccine toxicology studies in rodents, non-rodents, and NHPs for infectious disease and cancer immunotherapy vaccine IND submissions. - [Gene Therapy Preclinical Studies](https://iitri.org/gene-therapy-preclinical-studies/) - IITRI offers GLP toxicology, biodistribution, and immunophenotyping for gene therapy preclinical studies for IND submissions. - [COVID-19 Inhaled Drug Development](https://iitri.org/covid-19-inhaled-drug-development/) - Method development and aerosol delivery of potential COVID-19 drugs in efficacy studies against SARS-CoV-2 for multiple animal models in our ABSL-3 facilities. - [Test Article Lab](https://iitri.org/test-article-lab/) - The IITRI Test Article Lab has capabilities for multiple formulation types, compound types, and dosing routes for your studies. - [Biodistribution and Molecular Biology](https://iitri.org/biodistribution-and-molecular-biology/) - IITRI offers multiple methods and techniques for molecular biology including PCR and RT-qPCR, gene expression and transfection, and cloning. - [Resources](https://iitri.org/resources/) - Our scientists are experts in their respective fields of study and are highly published. We make these publications, presentations and white papers available to you, to assist in your research and development efforts. - [News](https://iitri.org/news/) - Check back often for news about IITRI's preclinical toxicology, inhalation toxicology, infectious disease, and bioanalytical services. - [Blog](https://iitri.org/blog/) - IITRI news and blogs about upcoming events and tradeshows, publications, and service highlights. - [Posters, White Papers, and Case Studies](https://iitri.org/posters-and-white-papers/) - IITRI frequently presents posters at scientific meetings, and we publish White Papers and Case Studies on specific preclinical study topics. - [Immuno-oncology Services](https://iitri.org/immuno-oncology-services/) - IITRI offers preclinical immuno-oncology translational models, characterization of immune responses, biodistribution, and GLP toxicology and safety studies. - [Carcinogenicity Studies](https://iitri.org/carcinogenicity-studies/) - GLP-compliant 2-year rodent carcinogenicity studies and 6-month studies in rasH2 transgenic mice, with access to large historical databases. - [Todd Bucciarelli](https://iitri.org/todd-bucciarelli/) - Todd Bucciarelli, MBA, is the VP for Business Development and Corporate Strategy. Experience within the biotech and drug development industries for15 years - [David McCormick](https://iitri.org/david-mccormick/) - David L. McCormick, PhD, DABT, is President Emeritus and Senior Advisor. He joined the IITRI staff in 1979 and served as Director of IITRI from 2002-2024. - [Robert Baker](https://iitri.org/robert-baker/) - Robert Baker, PhD, Senior VP and Director of IITRI, is an experienced virologist, microbiologist and molecular biologist. Formerly the Division Manager of MMB - [In Vivo GLP Inhalation Toxicology](https://iitri.org/in-vivo-glp-inhalation-toxicology/) - Inhalation toxicology studies including aerosol challenge, environmental risk assessments, occupational health studies, e-cig and tobacco. - [F. tularensis Mouse Bioaerosol Model](https://iitri.org/f-tularensis-mouse-bioaerosol-model/) - IITRl’s bioaerosol system has proven to be highly effective in generating & stabilizing aerosolized bacteria for the inhalation infection in vaccine studies - [Privacy Policy](https://iitri.org/privacy-policy/) - Read our privacy policy here about cookies and data collected. - [Clinical Trial Support](https://iitri.org/clinical-trial-support/) - Clinical trial support with GLP validated methods for bioanalysis of APIs with LC-MS/MS, GC-MS and vaccine trial support with HAI and MN assays. - [BSL-2 / BSL-3 Animal Studies](https://iitri.org/bsl-2-bsl-3-facility/) - Includes 10k sq ft of CDC-approved, BSL-2 and BSL-3 + space for in vitro and animal models for non-GLP and GLP efficacy and safety for even NHPs and inhalation - [Zika Mouse Pregnancy Model](https://iitri.org/zika-mouse-pregnancy-model/) - A Zika mouse pregnancy model is now available to evaluate the potential of experimental vaccines to prevent maternal-fetal Zika virus transmission and associated congenital defects. - [Zika Rhesus Macaque Model](https://iitri.org/zika-rhesus-macaque-model/) - IITRI has developed a Rhesus macaque Zika infection model for the preclinical testing of vaccines and antiviral therapeutics. - [BSL-3 Aerosol Challenge Studies](https://iitri.org/bsl-3-aerosol-challenge-studies/) - BSL-3 / ABSL-3 aerobiology lab includes an aerosol generation apparatus for aerosol challenge studies with pathogens, select agents or toxins (bioaerosols) - [Influenza Studies](https://iitri.org/influenza-studies/) - IITRI is a leading CRO for mouse and ferret influenza studies to evaluate vaccines, adjuvants and antiviral agents against seasonal and high-path strains. - [Vaccine and Antiviral Development](https://iitri.org/vaccine-and-antiviral-development/) - Vaccine development, GLP vaccine tox, and monitoring immune responses from viral and biologics for preclinical challenge studies and clinical trial support. - [Safety Pharmacology](https://iitri.org/safety-pharmacology/) - Core battery of GLP-compliant safety pharmacology studies for cardiovascular, respiratory, and central nervous system as standalone or repeat-dose toxicity - [Drug Discovery](https://iitri.org/drug-discovery/) - IITRI provides non-GLP studies analyzing exposure and toxicology of lead candidates, including pharmacokinetic (PK) and toxicology or immunogenicity. - [Inhalation Toxicology](https://iitri.org/inhalation-toxicology/) - Inhalation Toxicology. Preclinical inhalation toxicology CRO services IND safety and toxicology submissions, occupational health assessments, ecig studies. - [Brochures](https://iitri.org/brochures/) - Brochures are available for preclinical services from IITRI covering our capabilities, animal models, and service offerings as a premier CRO - [Quality Control and Quality Assurance](https://iitri.org/qualitycontrolandqualityassurance/) - IITRI has been performing GLP safety studies since the regulations were put in place in 1979. During this time we have performed thousands of GLP studies. - [Marmoset Studies for Preclinical Toxicology](https://iitri.org/marmoset-studies-preclinical-toxicology/) - IITRI has marmoset animal models available for preclinical GLP toxicology studies, immunogenicity studies, and infectious models like MERS-CoV - [Exposure Atmosphere Characterization](https://iitri.org/exposure-atmosphere-characterization/) - Test article aerosol generation service. Development and optimization of methods, characterization of test atmosphere, and concentration. - [Zika AG129 Mouse Model](https://iitri.org/zika-ag129-mouse-model/) - A Zika AG129 mouse model using the PRV ABC59 isolate of Zika virus from the current outbreak is now available from IITRI for testing the efficacy of potential vaccines or antiviral drug candidates. - [Toxicology Chemical Products](https://iitri.org/toxicology-chemical-products/) - IITRI offers a full range of toxicity testing services to support registration of chemical products to the US EPA and FDA, as well as submissions to other international regulatory agencies for REACH registration. - [Thomas Horn](https://iitri.org/thomas-horn/) - Thomas Horn, PhD, DABT, is the Manager of the Toxicology Division of IITRI running hundreds of acute, subchronic, carc, and repro studies. - [E-cigs and ENDS Products](https://iitri.org/e-cigs-and-ends-products/) - IITRI offers inhalation toxicology studies of e-cigarettes or ENDS, flavors, and components of vaping liquids in alternative or modified tobacco products. - [Animal Welfare](https://iitri.org/animal-welfare/) - IITRI is committed to providing the best possible environment for animals in our facility, and to the humane and ethical treatment of all species of animals in our care. - [Non-GLP Toxicology](https://iitri.org/non-glp-toxicology/) - IITRI offers non-GLP toxicology studies to screen for a drug candidate’s toxicology risks and assist with the design of GLP toxicology studies. - [Mouse Tumor Models](https://iitri.org/mouse-tumor-models/) - IITRI offers preclinical evaluation of the efficacy and toxicity of cancer immunotherapies using xenograft and syngeneic mouse tumor models. - [Infusion Toxicology](https://iitri.org/infusion-toxicology/) - IITRI's toxicology study team provides IV infusion dosing route for GLP infusion toxicology preclinical studies in both small and large animals. - [PK Studies](https://iitri.org/pk-studies/) - IITRI provides in vivo pharmacokinetic (PK) studies in rodents, dogs, minipigs, and nonhuman primates (NHPs), and in-house bioanalytical services. - [IITRI History](https://iitri.org/iitri-history/) - IITRI was founded in 1936 as the research arm of the Illinois Institute of Technology (IIT) and operates as an independent, not-for-profit preclinical CRO. - [COVID-19 K18-hACE2 Transgenic Mouse Model](https://iitri.org/covid-transgenic-mouse-model/) - The K18-hACE2 mouse model of SARS-CoV-2 infection is available for evaluating antiviral therapeutic agents and vaccines using strains like WA, Delta and Omicron - [COVID-19 Syrian hamster model](https://iitri.org/covid-19-syrian-hamster-model/) - Efficacy of potential antivirals in the Syrian hamster model of COVID-19 with multiple SARS-CoV-2 variants such as Delta and Omicron. Transmission available. - [COVID-19 Ferret Model](https://iitri.org/covid-ferret-model/) - Ferret model for SARS-CoV-2 studies focused on the upper respiratory effects or transmission studies for COVID-19. - [SARS-CoV-2 In Vitro Assays](https://iitri.org/sars-cov-2-in-vitro/) - In vitro testing of potential antivirals or serum against multiple relevant strains of SARS-CoV-2 in IC50 assay. Other viruses can be tested as well. - [Thank You](https://iitri.org/thank-you/) - [et_pb_section fb_built=”1″ custom_padding_last_edited=”off|desktop” admin_label=”Header” _builder_version=”3.23.3″ background_color=”#2a2e40″ use_background_color_gradient=”on” background_color_gradient_start=”rgba(42,46,64,0)” background_color_gradient_end=”#2a2e40″ background_color_gradient_type=”radial” background_color_gradient_end_position=”70%” background_color_gradient_overlays_image=”on” background_image=”https://iitri.org/wp-content/uploads/2019/10/typing_contact.jpg” custom_padding=”||0px” custom_padding_tablet=”0vw||” custom_padding_phone=”0vw||”][et_pb_row _builder_version=”3.25″ module_alignment=”left” custom_padding=”0|0px|0|0px|true|false”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_divider color=”rgba(255,255,255,0.31)” divider_style=”dashed” _builder_version=”3.17.2″][/et_pb_divider][/et_pb_column][/et_pb_row][et_pb_row custom_padding_last_edited=”on|tablet” _builder_version=”3.25″ max_width=”80%” custom_margin=”||” custom_padding=”||0||false|false” custom_padding_tablet=”||40px|0%” custom_padding_phone=”” use_custom_width=”on” width_unit=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”3.27.4″ text_font=”||||||||” header_font=”Oswald|300||on|||||” header_font_size=”7vw” header_letter_spacing=”0.35em” header_line_height=”1.2em” header_2_font=”Oswald|300||on|||||” header_2_font_size=”7vw” header_2_letter_spacing=”0.35em” header_2_line_height=”1.2em” header_3_font=”Oswald|||on|||||” header_3_font_size=”12px” header_3_letter_spacing=”1.5em” header_3_line_height=”2.4em” background_layout=”dark” max_width=”80%” - [hometest](https://iitri.org/hometest/) - [et_pb_section fb_built=”1″ custom_padding_last_edited=”off|desktop” admin_label=”Header” _builder_version=”3.23.3″ background_color=”#2a2e40″ use_background_color_gradient=”on” background_color_gradient_start=”rgba(42,46,64,0.34)” background_color_gradient_end=”#2a2e40″ background_color_gradient_type=”radial” background_color_gradient_direction_radial=”top right” background_color_gradient_end_position=”90%” background_color_gradient_overlays_image=”on” background_image=”https://iitri.org/wp-content/uploads/2019/08/scentist_1.jpg” background_position=”top_right” custom_padding=”||0px” custom_padding_tablet=”0vw||” custom_padding_phone=”0vw||”][et_pb_row module_class=” et_pb_row_fullwidth” _builder_version=”3.23.3″ width=”89%” width_tablet=”80%” width_last_edited=”on|desktop” max_width=”89%” max_width_tablet=”80%” max_width_last_edited=”on|desktop” mix_blend_mode=”overlay” make_fullwidth=”on”][et_pb_column type=”4_4″ _builder_version=”3.16″][et_pb_text _builder_version=”3.23.3″ text_font=”Oswald|||on|||||” text_text_color=”rgba(255,255,255,0.5)” text_font_size=”18vw” text_line_height=”0em” header_font=”Oswald|||on|||||” header_font_size=”40px” header_letter_spacing=”20px” text_orientation=”right” background_layout=”dark” custom_margin=”||0.2em” custom_margin_phone=”||0em” custom_margin_last_edited=”off|desktop” filter_blur=”5px” animation_style=”slide” animation_direction=”left” animation_duration=”2000ms” animation_intensity_slide=”2%” text_font_size_tablet=”30vw” text_font_size_last_edited=”on|desktop” header_font_size_tablet=”40px” header_font_size_phone=”30px” header_font_size_last_edited=”on|desktop”]IITRI[/et_pb_text][/et_pb_column][/et_pb_row][et_pb_row ## Categories - [Uncategorized](https://iitri.org/category/uncategorized/) - [Blog](https://iitri.org/category/blog/) - Blog Items - [Events](https://iitri.org/category/events/) - Event Items - [News](https://iitri.org/category/news/) - Posts by IITRI staff about conferences, articles in the public press, and other news items that are of interest. - [Publications and Press](https://iitri.org/category/publications-and-press/)