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David L. McCormick, PhD, DABT | President and Director
David L. McCormick, PhD, DABT, is President and Director of IITRI, and Professor of Biology at the Illinois Institute of Technology (IIT). Joining the IITRI staff in 1979 and the IIT faculty in 1982, Dr. McCormick has served as Director of IITRI since 2002. Dr. McCormick received his AB degree in Biology/Chemistry from Middlebury College, and his MS and PhD degrees in Environmental Medicine/Biology from New York University.
A board-certified toxicologist, Dr. McCormick’s primary research activities are in the areas of experimental toxicology, pharmacology, and carcinogenesis. Over the past 35 years, Dr. McCormick has served as Principal Investigator on approximately 50 grants and contracts awarded by the National Cancer Institute (NCI) and the National Institute of Environmental Health Sciences (NIEHS), with total funding awards of more than $80 million. He has also led a broad range of preclinical drug development programs for sponsors in the pharmaceutical and biotechnology industries.
Dr. McCormick has published more than 250 research papers, abstracts, reviews, and book chapters. He is currently a member of the Editorial Boards of three scientific journals (Toxicology, Nutrition and Cancer, and Public Library of Science–One), and regularly serves on review committees for the National Institutes of Health (NIH) and other funding agencies.
Professional affiliations include the American Association for Cancer Research, International Association for Breast Cancer Research, Society for Experimental Biology and Medicine, Society of Toxicology, Society of Toxicology (Midwest Regional Chapter), and Society of Toxicology (Carcinogenesis Specialty Section).
Miguel Muzzio, PhD, MBA | Vice President and Deputy Director, Manager of Analytical Chemistry Division
Miguel Muzzio, PhD, MBA, is the Vice President and Deputy Director of IITRI, in addition to his responsibilities as Manager of the Analytical Chemistry Division. Dr. Muzzio received his BS degree in Chemistry and Master Equivalent degree in Pharmaceutical Chemistry from the University of Uruguay (Montevideo, Uruguay), while receiving his PhD in Chemistry and MBA degrees from the University of Rhode Island (Kingston, RI). Dr. Muzzio has been a member of the IITRI staff since 2001, and has served as a Study Director for numerous analytical chemistry studies conducted at IITRI for government and commercial sponsors.
He has more than 25 years of experience developing and implementing methods for the analysis of drug substances and other organic compounds in drug products, biologic specimens, and other complex matrices. He also has extensive experience in the extraction, purification, and structural identification of small molecules, metabolites, impurities, and degradation products using chromatographic and spectrometric analytical techniques such as GC, GC/MS, HPLC, LC/MS, LC/MS/MS, NMR, and IR.
Dr. Muzzio’s accomplishments include optimizing analytical services operations at IITRI to meet high-throughput requirements of multi-million dollar governmental and commercial programs, and he has published over 35 research papers and abstracts.
Sridhar Jaligama, PhD, DABT | Deputy Division Manager of Inhalation Toxicology
Sridhar Jaligama, PhD, DABT, Deputy Division Manager of Inhalation Toxicology. He is a board-certified toxicologist with over 10 years of experience in the design and conduct of complex toxicology programs. He has broad experience as a Study Director in several areas of non-clinical toxicology and with a specific expertise in inhalation and respiratory toxicology. In this role, he has led the design and conduct of complex non-clinical toxicology studies in compliance with FDA GLP regulations. He has led acute, subchronic, and chronic inhalation studies performed via nose-only and whole body inhalation exposure routes, and is proficient at in-depth technical reviews, data interpretation, and report preparation in compliance with the regulatory guidelines.
In his previous roles, Dr. Jaligama has led multiple inhalation toxicology study teams in programs involving a wide range of test articles. He is experienced in coordinating and managing toxicology research projects involving cross-functional teams. In addition to conducting programs to meet regulatory requirements, Dr. Jaligama has led a team to develop and validate new capabilities in pulmonary function measurement; implemented a formal training program for technicians; and served as contributing scientist for several phases of GLP studies.
Dr. Jaligama has a deep understanding of FDA Tobacco Deeming Regulations and Pre-market Tobacco Application requirements, and has served as the single point of technical contact for large toxicology programs conducted in support of Pre-market Tobacco Applications to FDA. He is an author/co-author of more than 50 publications and posters/presentations.
Robert Baker, PhD | Assistant Vice President and Manager of Microbiology and Molecular Biology Division
Robert Baker, PhD, Assistant Vice President and Manager of the Division of Microbiology and Molecular Biology at IITRI, is an experienced virologist, microbiologist and molecular biologist having more than 20 years of experience in infectious disease research. Dr. Baker earned his BS in Molecular and Cellular Biology from the University of Arizona where he also earned his PhD in Molecular Biology and Biochemistry.
Dr. Baker oversees the infectious disease and biodefense program at IITRI that includes the operation of Animal Biosafety Level-2 and -3 (ABSL-2/3) containment laboratories for research conducted with highly pathogenic viruses, bacteria, and select agents. Dr. Baker’s background includes high-level positions at the US Army Medical Research Institute of Infectious Diseases (USAMRIID), the Centers for Disease Control and Prevention (CDC), and the American Type Culture Collection (ATCC). Before joining IITRI in 2015, Dr. Baker was Director of Preclinical Microbiology and Immunotoxicology for a major respiratory research CRO. As Director for Research and Development at ATCC, he was Principal Investigator on their Biodefense and Emerging Infections (BEI) and Influenza Reagent Resource (IRR) programs. His current research focus is infectious disease animal models, vaccine development, assessment of antiviral drug efficacy, quantitative gene expression in eukaryotic systems, and clinical trial support.
He has over 60 research publications, government reports and posters/presentations. Professional affiliations include the American Society for Microbiology, American Society for Virology, International Society for Antiviral Research, International Society for Infectious Diseases and the American Biological Safety Association.
William D. Johnson, PhD, DABT | Assistant Vice President and Manager of Toxicology Division
William D. Johnson, PhD, DABT, is Assistant Vice President and Manager of the Toxicology Division of IITRI. Dr. Johnson received his BS in Biology from the University of Wisconsin (UW)–Whitewater and his PhD in Experimental Pathology from UW–Madison. A board-certified toxicologist since 1989, Dr. Johnson’s primary research activities are in the areas of carcinogenesis, cancer prevention, and preclinical toxicology.
Dr. Johnson joined the IITRI staff in 1986 and over the past 25 years, he has served as a Study Director for acute, subchronic, carcinogenicity, and reproduction/teratology studies involving rodents, rabbits, dogs, and nonhuman primates, all utilizing multiple routes of compound administration. He has experience in the testing of drugs, biologics, agricultural and industrial chemicals, food products, natural products, and cosmetics, publishing more than 100 research papers and abstracts. Dr. Johnson has served as the Principal Investigator on several NIH contracts and is currently Co-Principal Investigator on a National Cancer Institute contract evaluating the “Preclinical Toxicology of Drugs Developed for Cancer Patients.”
Dr. Johnson is a member of the Society of Toxicology (SOT) and the American Association of Cancer Research (AACR), and served as the Chairman of the IITRI Institutional Animal Care and Use Committee (IACUC) from 1990 to 2012.
Glenn Miller, MS, RQAP-GLP, RAC, CMQ/OE | Assistant Vice President and Manager of Research Support Services
Glenn B. Miller, MS, RQAP-GLP, RAC, CMQ/OE, CQA, is Assistant Vice President and Manager for the Research Support Services group and the Quality Assurance Unit at IITRI. Mr. Miller received his BA degree from Lewis University (Romeoville, IL) and his MS in Environmental Management from the Stuart School of Business at IIT. He is a Registered Quality Assurance Professional in Good Laboratory Practices (Society of Quality Assurance) since 2003, Regulatory Affairs Certified (Regulatory Affairs Professional Society) since 2006, and a Certified Quality Manager in Organizational Excellence (American Society of Quality) since 2007.
Mr. Miller has over 30 years of diversified management background in the medical device and generic pharmaceutical industry, and more than 25 years of experience interacting with US regulators at both the district and center levels. He has over 10 years of experience in performing laboratory inspections and data and report audits to ensure compliance with Good Laboratory Practice (GLP) regulations (such as FDA, EPA/FIFRA, EPA/TSCA, OECD, and Japanese GLPs), and adherence to the protocol and written Standard Operating Procedures (SOPs). During his tenure at IITRI, Mr. Miller has developed, implemented, and oversees quality and regulatory systems that meet the requirements of US FDA, US EPA, ISO Standards, and other international standards.
Mr. Miller is a member of the American Society for Quality (ASQ), Society for Quality Assurance (SQA), Midwest Society for Quality Assurance (MWSQA), and the Regulatory Affairs Professional Society (RAPS).
Todd Bucciarelli, MBA | Assistant Vice President and Director of Business Development
Todd Bucciarelli, MBA, is the Assistant Vice President and Director of Business Development for IITRI. Mr. Bucciarelli has had roles in both executive management and business development within the biotech and drug development industries for over 15 years. He has extensive experience in preclinical development of small molecule and biologic drugs. He and his team work closely with sponsors, consultants and their manufacturing partners to ensure comprehensive IND-enabling programs are executed to meet both regulatory guidelines and timelines. Mr. Bucciarelli received his BS degree from the University of St. Francis and his MBA degree from Northern Illinois University. He is co-author of 3 US patents on protein expression technologies for biologics drug development.