zika animal models
Services
We are ready to answer your questions and provide guidance.
zika animal models
Services
We are ready to answer your questions and provide guidance.
zika Studies
IITRI offers three specialized Zika virus models for research and testing purposes: rhesus macaque (NHP) model, AG129 mouse model, and mouse pregnancy model.
NHP Model
RHESUS MACAQUE MODEL |
The Rhesus macaque Zika infection model for the preclinical testing of vaccines and antiviral therapeutics was developed due to their close evolutionary proximity to humans and the similarity of their physiology and immunology.
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MOUSE ModelS
AG129 MOUSE MODEL |
This AG 129 mouse model utilizes the PRV ABC59 Zika virus strain responsible for outbreaks in South and Central America. Key features include:
A wild-type mouse model using an IFN-receptor blocking antibody is also available for evaluating immune responses to vaccinations or prophylactic treatments. |
MOUSE PREGNANCY MODEL |
The Zika Mouse Pregnancy Model provides a crucial tool for researchers and pharmaceutical companies working on developing interventions to prevent the devastating effects of Zika virus infection during pregnancy
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The IITRI Advantage
- Scientific team and PhD study directors from a broad range of disciplines including virology, microbiology, immunology, molecular biology and toxicology
- BSL-2/3 labs and vivarium
- Personalized study design
- Efficacy and vaccine challenge studies through GLP toxicology studies for regulatory submission