ASM 2016 Poster: Rabbit Aerosol Model for B. anthracis
A new IITRI poster presented at the recent ASM Biodefense and Emerging Diseases 2016 meeting is now available.
In this poster, Winston Lin and colleagues describe the development of an aerosol model of infection for B anthracis in rabbits using a modified 64-port inhalation nose-only exposure chamber with nebulizers. This platform produced consistent spray factors across concentrations. And, with capability for up to 8 rabbits, the platform potentially reduces variability in aerosol concentration delivery and minimizes the number of runs needed for a therapeutic or vaccine study.
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