IITRI now offers three different animals depending on the specifications and needs of your study.
Transgenic mouse model:
– K18-hACE2 transgenic mouse model
– Clinical signs such as body weight loss, mortality
– Viral load in nasal washes
Ferret model:
– Favorable model for looking at effects solely in upper respiratory tract
– Infection model only, no clinical signs
– Viral load and shedding in nasal washes
– Routes of dosage admin include intranasal, intraperitoneal, inhaled (inhalation), and intravenous
Syrian hamster model:
– Clinical signs such as body weight loss, although no mortality
– Viral load in nasal washes and blood
– Routes of dosage admin include intranasal, inhaled (inhalation), and intraperitoneal
– Virus detection in various tissues
For more information about the SARS-CoV-2 assays and tests we currently offer, click here. Our team would love to speak to anyone looking to test their candidates, contact us today!
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