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Service Spotlight: Exposure Atmosphere Characterization
STARTING OFF ON THE RIGHT FOOT Our inhalation services include preliminary method development activities as the necessary first step for inhalation toxicology studies. The selection and characterization of the test atmosphere to be realistic and extensively measured...
New Partner Publications- Promising COVID-19 Studies
IITRI is proud to share the promising news from multiple sponsors of COVID-19 in vitro and in vivo studies. Links below to press releases and recent publications. Congrats all! New IITRI Co-Author Publication: Scalable live-attenuated SARS-CoV-2 vaccine...
SARS-CoV-2 Variants of Concern Now Available
IITRI now has access to multiple SARS-CoV-2 variants. Currently available: B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma). Available soon: B.1.617.1 (Kappa) and B.1.617.2 (Delta) These variants are available for use in our assays (immunostain and neutralization) as well...
Division Spotlight: Inhalation Toxicology
Spread the Word: IITRI has 40+ Years of Experience in GLP Inhalation Studies Many inhalation professionals are unaware that IITRI provides complete end-to-end inhalation toxicology study programs for IND and NDA submissions. We have decades of expertise in aerosol...
Immunostain SARS-CoV-2 Efficacy Assay Available
IITRI now offers an improved efficacy assay for looking at effects of drugs on SARS-CoV-2. Although this assay no longer includes a cytotoxicity readout, we offer a neutral red assay in BSl-2 instead if needed. This current assay uses immunostaining and provides more...
IITRI offering the hACE2 mouse model for COVID-19
IITRI now offers three different animals depending on the specifications and needs of your study. Transgenic mouse model: – K18-hACE2 transgenic mouse model - Clinical signs such as body weight loss, mortality – Viral load in nasal washes Ferret model: –...
American College of Toxicology (Virtual) 41st Meeting
Even though we were saddened to hear that the 41st Annual Meeting of the American College of Toxicology (Nov 12-19) will not take place in the wonderful city of Austin this year, we support this decision and are very much looking forward to participating in the...
Hamster and ferret models available for COVID-19 studies
Ferret infection model: Since early in the pandemic, IITRI has been working on developing new animal models to test out therapeutics and treatments for COVID-19 (in addition to in vitro offerings of efficacy assays, neutralization assays, and surface decontaminant...
Promising antiviral activity of Moleculin’s drug candidate
IITRI is proud to share the promising news of one of our partners, Moleculin! Our team here at IITRI was contracted to perform additional in vitro testing of their drug candidate (WP1122) for antiviral effects against SARS-CoV-2. We used growth medium that more...
IITRI is testing antivirals and vaccines for COVID-19 | CRO
IITRI is now in custody of the a SARS-CoV-2 strain responsible for COVID-19. Our team is working on characterizing the strain for in vitro studies and in vivo modeling to test current vaccines and antivirals in addition to developing new treatments for this...
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